Spironolactone is an anti-androgen medication commonly prescribed for PCOS-related acne, hirsutism, and hair loss.
How it works: Spironolactone blocks androgen receptors and reduces androgen production. It was originally developed as a blood pressure medication (it's a diuretic), but its anti-androgen effects made it valuable for PCOS.
What it can improve:
• Hormonal acne (especially jawline and chin) — typically visible improvement in 3-6 months • Hirsutism — slows new hair growth (existing hair needs removal methods) • Androgenic hair loss — may slow or partially reverse thinning
Timeline: Skin improvements usually take 3-6 months. Hair changes take 6-12 months. This is a slow-acting medication — patience is essential.
Common side effects: • Increased urination (it's a diuretic) • Dizziness, especially when standing up quickly • Breast tenderness • Irregular periods (often prescribed alongside birth control for this reason) • Elevated potassium — regular blood tests are important
CRITICAL SAFETY INFORMATION: • Spironolactone is ABSOLUTELY UNSAFE during pregnancy. It can cause severe birth defects (feminisation of a male fetus). • Reliable contraception is mandatory while taking it. • Stop well before attempting conception (discuss timeline with your doctor).
Despite the safety considerations, spironolactone is one of the most effective treatments for androgen-related PCOS symptoms. Typical doses range from 50-200mg daily.